November 24, 2008

Real-time chemical responses in the nucleus accumbens differentiate rewarding and aversive stimuli

neurochemistry,neuroscience,perception — alice @ 1:28 am Print This Post  AddThis Social Bookmark Button

Mitchell F Roitman, Robert A Wheeler, R Mark Wightman and Regina M Carelli
Article in Nature Neuroscience

Abstract
Rewarding and aversive stimuli evoke very different patterns of behavior and are rapidly discriminated. Here taste stimuli of opposite hedonic valence evoked opposite patterns of dopamine and metabolic activity within milliseconds in the nucleus accumbens. This rapid encoding may serve to guide ongoing behavioral responses and promote plastic changes in underlying circuitry.

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